Injectable Bulking Agents for the Treatment of Stress Urinary Incontinence

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A new injectable bulking agent for treatment of stress urinary incontinence.

OBJECTIVES To assess the safety and effectiveness of Durasphere compared with bovine collagen in the treatment of stress urinary incontinence (SUI) due to intrinsic sphincter deficiency (ISD). METHODS This multicenter, randomized, controlled, double-blind trial was composed of 355 women diagnosed with SUI due to ISD and used a standardized pad test and the Stamey continence grade as the prima...

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Bulking agents for urinary incontinence: what, when and where?

Stress urinary incontinence is a major problem at the field of female urology and urogynecology. Symptomatically, this is a losing of the urine on physical efforts, coughing or sneezing. Incompetency of the urethral closing mechanisms are causing urine loss. Mid-urethral synthetic slings are the gold standard of the treatment of the stress urinary incontinence. At the same time, different ureth...

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Injectable anal bulking agent for the management of faecal incontinence.

This study was conducted to determine the safety and efficacy of injectable bulking agents. A total of 13 procedures were performed on 11 patients with faecal incontinence during 2002 to 2007. Patients with internal anal sphincter defect and low incontinence score (Cleveland score < 10) revealed improvement. Patients with higher incontinence score and external sphincter defect secondary to obst...

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Bioactive porous beads as an injectable urethral bulking agent: in vivo animal study for the treatment of urinary incontinence.

In our previous study, growth factor (basic fibroblast growth factor [bFGF] or vascular endothelial growth factor)-immobilized polycaprolactone (PCL)/Pluronic F127 porous beads were fabricated by an isolated particle-melting/melt-molding particulate-leaching method. The growth factors were easily immobilized onto the pore surfaces of the PCL/F127 beads via heparin binding, and were continuously...

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Objective. To evaluate the efficacy and safety of the new injectable implant, Urolastic, in women with stress urinary incontinence (SUI) after 12-month followup. Materials and Methods. A prospective, cohort study included adult women with SUI. Patients were treated with Urolastic periurethral injections under local anaesthesia. The injection procedure was repeated after 6 weeks when indicated. ...

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ژورنال

عنوان ژورنال: SM Gerontology and Geriatric Research

سال: 2017

ISSN: 2576-5434

DOI: 10.36876/smggr.1005